We have noticed a few issues with AirWatch on version 8.4.5 and 8.4.8
The screen layout issue with 8.4.5 was dealing with the dock layout, where certain apps ( i.e MS one Drive) will not go onto dock. Solution for us was to create a new layout profile with just dock configure, plus the first page, save the profile and then update the profile for the layout of the rest pages.
The issue with 8.4.8 was due to app icon images format, where there maybe an issue with image format whitelisting on the data base( this is also the walk around where whitelisting of image format will fix the issue). When issue occur, you will not be able to publish any app, unless the app icon image is removed.